STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glgAGlycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (650 aa)    
Predicted Functional Partners:
glgB
Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.995
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.994
Isop_1198
Glucose-1-phosphate adenylyltransferase; COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR011831: IPR005835: IPR005836; KEGG: plm:Plim_1974 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; SPTR: Glucose-1-phosphate adenylyltransferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.993
glgE
Glycosyl transferase group 1; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
  
 
 0.955
Isop_1552
4-alpha-glucanotransferase; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR015178: IPR004300: IPR015179; KEGG: psl:Psta_3212 4-alpha-glucanotransferase; PFAM: Domain of unknown function DUF1926; Domain of unknown function DUF1925; glycoside hydrolase family 57; PRIAM: 4-alpha-glucanotransferase; SPTR: Alpha-amylase; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926).
  
 
  0.913
Isop_2464
COGs: COG1543 conserved hypothetical protein; KEGG: noc:Noc_0099 glycoside hydrolase family protein; SPTR: Glycoside hydrolase, family 57.
  
 
  0.908
Isop_1901
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: afw:Anae109_1425 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase, group 1 family protein; PFAM: Glycosyl transferases group 1.
     
  0.900
Isop_3628
COGs: COG0058 Glucan phosphorylase; InterPro IPR011834: IPR000811; KEGG: psl:Psta_1121 alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: Alpha-glucan phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases.
 
  
 0.882
Isop_1028
Maltooligosyl trehalose hydrolase; COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR006589: IPR012768: IPR004193: IPR006047; KEGG: cyb:CYB_2529 malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: Malto-oligosyltrehalose trehalohydrolase; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: malto-oligosyltrehalose trehalohydrolase.
  
  
 0.761
Isop_0445
Isoamylase; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR004193: IPR006047: IPR006589: IPR011837; KEGG: dak:DaAHT2_1644 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase [...]
  
  
 0.729
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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