Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2019InterPro IPR004360; KEGG: cvi:CV_2020 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Putative uncharacterized protein; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. (151 aa)    
Predicted Functional Partners:
Isop_2802
Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: psl:Psta_3932 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
     
  0.900
Isop_3580
Hypothetical protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: dae:Dtox_2285 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
     
  0.900
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
  0.807
Isop_2698
COGs: COG1760 L-serine deaminase; InterPro IPR005131: IPR005130: IPR004644; KEGG: mpt:Mpe_A1429 L-serine ammonia-lyase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; SPTR: L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form.
     
  0.800
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.800
Isop_3461
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG1171 Threonine dehydratase; InterPro IPR001926: IPR000634; KEGG: scl:sce3847 putative serine/threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Putative serine/threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme.
    
  0.800
Isop_1747
COGs: COG1966 Carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: kra:Krad_4167 carbon starvation protein CstA; PFAM: carbon starvation protein CstA; SPTR: Carbon starvation protein CstA; PFAM: Carbon starvation protein CstA.
   
    0.486
Isop_0503
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: svi:Svir_35400 NAD-dependent protein deacetylase, SIR2 family; PFAM: Silent information regulator protein Sir2; SPTR: NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family.
  
    0.422
Isop_1139
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: scl:sce7444 NAD-dependent deacetylase; PFAM: Silent information regulator protein Sir2; SPTR: Transcriptional regulatory protein, Sir2 family; manually curated; PFAM: Sir2 family.
  
    0.422
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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