STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2050Trehalose synthase; COGs: COG0366 Glycosidase; InterPro IPR006047: IPR006589: IPR012810; KEGG: mxa:MXAN_3684 trehalose synthase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Trehalose synthase; TIGRFAM: trehalose synthase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: trehalose synthase. (549 aa)    
Predicted Functional Partners:
Isop_2852
Aminoglycoside phosphotransferase; COGs: COG3281 Uncharacterized protein probably involved in trehalose biosynthesis; InterPro IPR002575; KEGG: afw:Anae109_3070 1,4-alpha-glucan branching enzyme; PFAM: aminoglycoside phosphotransferase; SPTR: 1,4-alpha-glucan branching enzyme; manually curated; TIGRFAM: trehalose synthase-fused probable maltokinase.
 
 0.992
Isop_1029
COGs: COG3280 Maltooligosyl trehalose synthase; InterPro IPR006589: IPR012767: IPR004300: IPR006047; KEGG: cag:Cagg_2094 maltooligosyl trehalose synthase; PFAM: alpha amylase catalytic region; glycoside hydrolase family 57; SMART: alpha amylase catalytic sub domain; SPTR: Malto-oligosyltrehalose synthase; TIGRFAM: malto-oligosyltrehalose synthase; PFAM: Alpha amylase, catalytic domain; Glycosyl hydrolase family 57; Domain of unknown function (DUF3536); TIGRFAM: malto-oligosyltrehalose synthase.
 
 
 0.982
Isop_1028
Maltooligosyl trehalose hydrolase; COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR006589: IPR012768: IPR004193: IPR006047; KEGG: cyb:CYB_2529 malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: Malto-oligosyltrehalose trehalohydrolase; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: malto-oligosyltrehalose trehalohydrolase.
 
 
 0.977
Isop_2400
Isoamylase; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR006589: IPR011837: IPR004193: IPR006047; KEGG: dak:DaAHT2_0475 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase [...]
 
 
0.940
Isop_0445
Isoamylase; COGs: COG1523 Type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR004193: IPR006047: IPR006589: IPR011837; KEGG: dak:DaAHT2_1644 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase [...]
  
 
0.936
glgB
Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 
0.934
Isop_3628
COGs: COG0058 Glucan phosphorylase; InterPro IPR011834: IPR000811; KEGG: psl:Psta_1121 alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; PRIAM: Phosphorylase; SPTR: Alpha-glucan phosphorylase; TIGRFAM: alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; Protein of unknown function (DUF3417); TIGRFAM: alpha-glucan phosphorylases.
  
 0.930
Isop_2464
COGs: COG1543 conserved hypothetical protein; KEGG: noc:Noc_0099 glycoside hydrolase family protein; SPTR: Glycoside hydrolase, family 57.
     
 0.909
Isop_1552
4-alpha-glucanotransferase; COGs: COG1449 Alpha-amylase/alpha-mannosidase; InterPro IPR015178: IPR004300: IPR015179; KEGG: psl:Psta_3212 4-alpha-glucanotransferase; PFAM: Domain of unknown function DUF1926; Domain of unknown function DUF1925; glycoside hydrolase family 57; PRIAM: 4-alpha-glucanotransferase; SPTR: Alpha-amylase; PFAM: Domain of unknown function (DUF1925); Glycosyl hydrolase family 57; Domain of unknown function (DUF1926).
    
 0.906
glgE
Glycosyl transferase group 1; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
  
 
   0.771
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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