Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2059Oligoendopeptidase, M3 family; COGs: COG1164 Oligoendopeptidase F; InterPro IPR001567: IPR011976; KEGG: min:Minf_1983 oligoendopeptidase F; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; SPTR: Oligoendopeptidase, M3 family; TIGRFAM: oligoendopeptidase, M3 family; PFAM: Peptidase family M3; TIGRFAM: oligoendopeptidase, M3 family. (573 aa)    
Predicted Functional Partners:
Isop_0660
COGs: COG0015 Adenylosuccinate lyase; InterPro IPR000362: IPR019468: IPR004769: IPR020557; KEGG: plm:Plim_3831 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
    0.478
Isop_0754
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
    0.473
Isop_1590
Phosphoesterase; COGs: COG3391 conserved hypothetical protein; InterPro IPR007312; KEGG: sli:Slin_6217 40-residue YVTN family beta-propeller repeat protein; PFAM: phosphoesterase; SPTR: 40-residue YVTN family beta-propeller repeat protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; Phosphoesterase family; 3-carboxy-cis,cis-muconate lactonizing enzyme.
 
     0.427
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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