STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2124Metal dependent phosphohydrolase; COGs: COG3481 HD-superfamily hydrolase; InterPro IPR003607: IPR006674; KEGG: psl:Psta_4761 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Nucleic acid-binding protein, putative; PFAM: HD domain. (375 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
  
    0.683
Isop_2125
Hypothetical protein; InterPro IPR001120: IPR012902; KEGG: plm:Plim_4084 protein of unknown function DUF1559; SPTR: Putative uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; Protein of unknown function (DUF1559); TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
       0.447
Isop_2123
KEGG: tit:Thit_1395 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.429
Isop_1315
Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: nmu:Nmul_A2462 rhomboid-like protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein; PFAM: Rhomboid family.
  
     0.412
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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