STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2125Hypothetical protein; InterPro IPR001120: IPR012902; KEGG: plm:Plim_4084 protein of unknown function DUF1559; SPTR: Putative uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; Protein of unknown function (DUF1559); TIGRFAM: prepilin-type N-terminal cleavage/methylation domain. (327 aa)    
Predicted Functional Partners:
Isop_1114
Type II and III secretion system protein; COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR019734: IPR001440: IPR004846; KEGG: plm:Plim_0641 hypothetical protein; PFAM: type II and III secretion system protein; Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Putative uncharacterized protein; PFAM: Bacterial type II and III secretion system protein.
  
    0.662
Isop_2201
KEGG: rba:RB6430 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.598
Isop_1036
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR005883; KEGG: plm:Plim_0076 type IV pilus assembly protein PilM; SPTR: Probable fimbrial assembly protein PilM; TIGRFAM: type IV pilus assembly protein PilM; PFAM: Competence protein A; Cell division protein FtsA; TIGRFAM: type IV pilus assembly protein PilM.
 
     0.580
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.551
Isop_0849
KEGG: psl:Psta_2453 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.532
Isop_0202
KEGG: plm:Plim_3249 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.530
Isop_0433
COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterPro IPR007627: IPR007630: IPR014284: IPR000943; KEGG: psl:Psta_2560 RNA polymerase, sigma 32 subunit, RpoH; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
  
     0.530
Isop_2618
InterPro IPR003400; KEGG: plm:Plim_3761 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR.
  
     0.501
Isop_3426
KEGG: plm:Plim_3751 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.495
Isop_1769
KEGG: rba:RB11569 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.483
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.