| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Isop_0047 | msrA | Isop_0047 | Isop_0249 | Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR017936; KEGG: plm:Plim_0535 cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region; Protein of unknown function, DUF255. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.772 |
| Isop_0047 | msrB | Isop_0047 | Isop_2128 | Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR017936; KEGG: plm:Plim_0535 cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region; Protein of unknown function, DUF255. | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | 0.772 |
| msrA | Isop_0047 | Isop_0249 | Isop_0047 | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR017936; KEGG: plm:Plim_0535 cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region; Protein of unknown function, DUF255. | 0.772 |
| msrA | msrB | Isop_0249 | Isop_2128 | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | 0.990 |
| msrB | Isop_0047 | Isop_2128 | Isop_0047 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR017936; KEGG: plm:Plim_0535 cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region; Protein of unknown function, DUF255. | 0.772 |
| msrB | msrA | Isop_2128 | Isop_0249 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.990 |
| msrB | queC | Isop_2128 | Isop_1692 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.682 |
| msrB | rplK | Isop_2128 | Isop_0109 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.558 |
| msrB | rplL | Isop_2128 | Isop_0106 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.558 |
| msrB | rplT | Isop_2128 | Isop_0477 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.576 |
| msrB | rplU | Isop_2128 | Isop_1593 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.558 |
| msrB | rpmA | Isop_2128 | Isop_1691 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | COGs: COG0211 Ribosomal protein L27; InterPro IPR001684: IPR018261; KEGG: plm:Plim_0238 ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.558 |
| msrB | rpmG | Isop_2128 | Isop_0112 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | LSU ribosomal protein L33P; InterPro IPR001705; KEGG: plm:Plim_0436 ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; Belongs to the bacterial ribosomal protein bL33 family. | 0.575 |
| msrB | rpmJ | Isop_2128 | Isop_2100 | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | LSU ribosomal protein L36P; InterPro IPR000473; KEGG: ele:Elen_2808 ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; Belongs to the bacterial ribosomal protein bL36 family. | 0.618 |
| queC | msrB | Isop_1692 | Isop_2128 | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | 0.682 |
| queC | rpmA | Isop_1692 | Isop_1691 | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | COGs: COG0211 Ribosomal protein L27; InterPro IPR001684: IPR018261; KEGG: plm:Plim_0238 ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. | 0.461 |
| rplK | msrB | Isop_0109 | Isop_2128 | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase. | 0.558 |
| rplK | rplL | Isop_0109 | Isop_0106 | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.993 |
| rplK | rplT | Isop_0109 | Isop_0477 | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.965 |
| rplK | rplU | Isop_0109 | Isop_1593 | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.967 |