STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2159COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635: IPR002290: IPR017441: IPR008271: IPR 017442: IPR005532: IPR000719; KEGG: psl:Psta_0057 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; protein of unknown function DUF323; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Probable serine/threonine-protein kinase pknB; PFAM: Protein kinase domain; Formylglycine-generating sulfatase enzyme. (747 aa)    
Predicted Functional Partners:
Isop_3386
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045: IPR001932; KEGG: plm:Plim_2397 phosphoprotein phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; SPTR: Protein phosphatase; PFAM: Protein phosphatase 2C.
 
 
 0.821
Isop_3004
COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932: IPR014045: IPR010822; KEGG: psl:Psta_1567 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C.
 
 
 0.812
Isop_1821
KEGG: plm:Plim_2849 tyrosine protein kinase; SPTR: Tyrosine protein kinase.
  
    0.560
Isop_0098
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR019782: IPR017986: IPR017441: IPR 008271: IPR019775: IPR017442: IPR019781: IPR020635: IPR002290:I PR001680; KEGG: psl:Psta_3450 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase; PFAM: Protein kinase domain; WD domain, G-beta repeat.
 
   
0.420
Isop_0068
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR019782: IPR017986: IPR006530: IPR 017441: IPR008271: IPR019775: IPR017442: IPR019781: IPR020635:I PR002290: IPR001680; KEGG: psl:Psta_3450 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase; TIGRFAM: YD repeat protein; PFAM: Protein kinase domain; WD domain, G-beta repeat; TIGRFAM: YD repeat (two copies).
 
   
0.418
Isop_1638
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR019782: IPR017986: IPR017441: IPR 008271: IPR020635: IPR002290: IPR001680: IPR017442: IPR019781; KEGG: sro:Sros_7190 WD40 repeat-domain-containing protein-like protein; PFAM: Serine/threonine-protein kinase-like domain; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; WD-40 repeat-containing protein; SPTR: WD40 repeat-domain-containing protein-like protein; PFAM: Protein kinase domain; WD domain, G-beta repeat.
 
   
0.418
Isop_1637
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR019782: IPR017986: IPR020472: IPR 017441: IPR008271: IPR019775: IPR020635: IPR002290: IPR001680:I PR017442: IPR019781; KEGG: tcu:Tcur_0419 serine/threonine protein kinase with WD40 repeats; PFAM: Serine/threonine-protein kinase-like domain; WD40 repeat, subgroup; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; WD-40 repeat-containing protein; SPTR: Serine/threonine protein kinase with WD40 repeats; PFAM: Protein kinase domain; WD domain, G-beta repeat.
 
   
0.415
Isop_2049
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000253: IPR017442: IPR020635: IPR002290: IPR 017441: IPR008271: IPR000719; KEGG: sro:Sros_3456 serine/threonine protein kinase-like protein; PFAM: Serine/threonine-protein kinase-like domain; Forkhead-associated protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; Forkhead-associated protein; SPTR: Serine/threonine protein kinase-like protein; PFAM: Protein kinase domain; FHA domain.
 
  
0.413
Isop_2160
Secretion protein HlyD family protein; InterPro IPR003997: IPR006143; KEGG: rba:RB10473 alkaline protease secretion protein AprE; PFAM: secretion protein HlyD family protein; SPTR: Similar to alkaline proteinase secretion protein aprE.
       0.410
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.