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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Isop_2238InterPro IPR019734: IPR001440: IPR013026; KEGG: ade:Adeh_3311 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR domain protein. (1601 aa)    
Predicted Functional Partners:
Isop_2239
Exosortase EpsH-related protein; InterPro IPR019127; KEGG: rba:RB2461 hypothetical protein; PFAM: Exosortase EpsH-related; SPTR: Putative uncharacterized protein; PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: eight transmembrane protein EpsH (proposed exosortase).
 
     0.874
lpxC
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
   
 
 0.856
Isop_2240
Hypothetical protein; KEGG: azl:AZL_027420 UvrD/REP helicase; SPTR: SNF2-related protein.
       0.773
Isop_1922
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR001098: IPR002421: IPR 008918: IPR002298: IPR018320: IPR019760; KEGG: plm:Plim_3011 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; SMART: DNA-directed DNA polymerase; 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polym [...]
  
    0.769
Isop_3676
Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG0457 FOG: TPR repeat; InterPro IPR019734: IPR013026: IPR001440; KEGG: pcs:Pc22g03720 Pc22g03720; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Pc22g03720 protein; PFAM: Tetratricopeptide repeat.
 
 
 
 0.646
Isop_1958
PDZ/DHR/GLGF domain protein; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001940; KEGG: psl:Psta_3797 peptidase S1 and S6 chymotrypsin/Hap; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF).
   
 
 0.639
Isop_3042
Eight transmembrane protein EpsH; InterPro IPR013426: IPR019127; KEGG: dvl:Dvul_3054 eight transmembrane protein EpsH; PFAM: Exosortase EpsH-related; SPTR: Eight transmembrane protein EpsH; TIGRFAM: eight transmembrane protein EpsH; PFAM: Transmembrane exosortase (Exosortase_EpsH); TIGRFAM: eight transmembrane protein EpsH (proposed exosortase).
 
     0.585
Isop_1972
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013767: IPR003661: IPR003594: IPR 001789: IPR008207: IPR000014: IPR004358: IPR000896: IPR005467; KEGG: rba:RB159 sensory transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine k [...]
     
 0.568
Isop_2651
Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR019734: IPR013026: IPR001440; KEGG: plm:Plim_4208 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Putative uncharacterized protein.
 
 
 
 0.527
Isop_1153
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789: IPR003661: IPR003594: IPR005467: IPR 004358; KEGG: dsa:Desal_1726 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Hpt sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
     
 0.524
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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