STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2248COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR017937: IPR006662: IPR013766: IPR017936; KEGG: psl:Psta_1606 thioredoxin domain protein; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin domain protein; PFAM: Thioredoxin; TIGRFAM: thioredoxin. (286 aa)    
Predicted Functional Partners:
Isop_0020
COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR000103: IPR013027: IPR008255; KEGG: acp:A2cp1_4094 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
  
 
 0.694
Isop_1592
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.622
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.618
groL-2
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.618
groL-3
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.618
Isop_3417
COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR006070: IPR017867: IPR000106; KEGG: plm:Plim_2592 protein-tyrosine phosphatase, low molecular weight; PFAM: Protein-tyrosine phosphatase, low molecular weight; SUA5/yciO/yrdC domain; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein-tyrosine phosphatase, low molecular weight; PFAM: Low molecular weight phosphotyrosine protein phosphatase; yrdC domain; Belongs to the SUA5 family.
  
 
 0.594
Isop_2214
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583: IPR006982: IPR002932: IPR002489: IPR 017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
   
 
 0.584
Isop_2419
YD repeat protein; COGs: COG3209 Rhs family protein; InterPro IPR003587: IPR006530: IPR006141; KEGG: plm:Plim_1036 AmoP; PFAM: YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: AmoP; TIGRFAM: YD repeat protein; PFAM: RHS Repeat; Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain; YD repeat (two copies).
    
   0.563
Isop_2572
KEGG: chu:CHU_1515 protein-tyrosine-phosphatase; SPTR: Probable arsenate reductase.
  
 
 0.556
Isop_3519
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR006424: IPR020831: IPR020828: IPR020829: IPR 020832: IPR020830; KEGG: plm:Plim_0647 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Strongly similar to glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phospha [...]
  
 
 0.508
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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