STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2258Amidohydrolase 3; COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: scl:sce3068 putative secreted protein; PFAM: Amidohydrolase 3; SPTR: Putative lipoprotein; PFAM: Amidohydrolase family. (552 aa)    
Predicted Functional Partners:
hisE
COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; InterPro IPR008179: IPR021130; KEGG: psl:Psta_4703 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase.
       0.594
Isop_1893
Acylaminoacyl-peptidase; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR011659; KEGG: kko:Kkor_1452 peptidase S9 prolyl oligopeptidase active site domain protein; PFAM: WD40-like beta Propeller containing protein; PRIAM: Acylaminoacyl-peptidase; SPTR: Putative uncharacterized protein; PFAM: Prolyl oligopeptidase family.
 
     0.579
Isop_3297
InterPro IPR000834; KEGG: sus:Acid_1533 peptidase M14, carboxypeptidase A; PFAM: peptidase M14 carboxypeptidase A; SPTR: Peptidase M14, carboxypeptidase A; PFAM: Zinc carboxypeptidase.
 
     0.577
Isop_1051
COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: sus:Acid_4848 beta-lactamase; PFAM: beta-lactamase; SPTR: Beta-lactamase; PFAM: Beta-lactamase.
 
     0.524
Isop_1883
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: rbi:RB2501_14084 probable aminopeptidase; PFAM: peptidase M28; SPTR: Peptidase M28; PFAM: Peptidase family M28.
  
     0.475
Isop_0183
WD40-like beta Propeller containing protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR011659; KEGG: mxa:MXAN_6601 S9C family peptidase; PFAM: WD40-like beta Propeller containing protein; SPTR: Prolyl oligopeptidase family protein; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat.
 
     0.472
Isop_1257
Amidohydrolase 3; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR013108; KEGG: swi:Swit_0080 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Putative uncharacterized protein; PFAM: Amidohydrolase family.
  
     0.457
Isop_0277
COGs: COG3653 N-acyl-D-aspartate/D-glutamate deacylase; InterPro IPR013108: IPR012855; KEGG: sro:Sros_1552 N-acyl-D-glutamate deacylase; PFAM: D-aminoacylase domain protein; Amidohydrolase 3; PRIAM: N-acyl-D-glutamate deacylase; SPTR: N-acyl-D-glutamate deacylase; PFAM: D-aminoacylase, C-terminal region; Amidohydrolase family.
 
     0.438
Isop_0972
Peptidase M28; COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: nde:NIDE3566 putative peptidase; PFAM: peptidase M28; SPTR: Aminopeptidase; PFAM: Peptidase family M28.
  
     0.436
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.