STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_2260COGs: COG3970 Fumarylacetoacetate (FAA) hydrolase family protein; InterPro IPR002529; KEGG: scl:sce8243 fumarylacetoacetase family protein; PFAM: fumarylacetoacetate (FAA) hydrolase; SPTR: Fumarylacetoacetase family protein; PFAM: Fumarylacetoacetate (FAA) hydrolase family. (303 aa)    
Predicted Functional Partners:
Isop_3339
Dehydratase, YjhG/YagF family; COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR017798: IPR000581: IPR020558; KEGG: psl:Psta_2493 dehydratase, YjhG/YagF family; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dehydratase, YjhG/YagF family; TIGRFAM: dehydratase, YjhG/YagF family; PFAM: Dehydratase family; TIGRFAM: probable dehydratase, YjhG/YagF family; Belongs to the IlvD/Edd family.
 
  
 0.934
Isop_0658
Ureidoglycolate lyase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: plm:Plim_1770 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
 
     0.691
Isop_0176
Ureidoglycolate lyase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: rme:Rmet_5199 fumarylacetoacetate hydrolase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family.
 
     0.679
Isop_2259
KEGG: psl:Psta_2862 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: Copper type II ascorbate-dependent monooxygenase, C-terminal domain.
 
     0.477
Isop_2013
COGs: COG3386 Gluconolactonase; InterPro IPR000801: IPR013658: IPR005511; KEGG: plm:Plim_2162 SMP-30/gluconolaconase/LRE domain protein; PFAM: SMP-30/Gluconolaconase/LRE-like region-containing protein; esterase; SPTR: SMP-30/Gluconolaconase/LRE domain protein; PFAM: SMP-30/Gluconolaconase/LRE-like region; Putative esterase.
 
     0.475
Isop_0758
KEGG: rba:RB6409 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3500).
  
     0.447
Isop_2725
KEGG: ote:Oter_0116 putative acetyl xylan esterase; SPTR: Probable acetyl xylan esterase.
  
     0.428
Isop_2380
Membrane-bound dehydrogenase domain protein; COGs: COG3828 conserved hypothetical protein; InterPro IPR013428: IPR013427: IPR009056; KEGG: psl:Psta_1431 membrane-bound dehydrogenase domain protein; SPTR: Membrane-bound dehydrogenase domain protein; TIGRFAM: membrane-bound dehydrogenase domain protein; heme-binding protein; PFAM: Cytochrome c; Trehalose utilisation; Membrane bound L-sorbosone dehydrogenase; TIGRFAM: putative membrane-bound dehydrogenase domain; putative heme-binding domain, Pirellula/Verrucomicrobium type.
  
     0.403
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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