STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2274Protein of unknown function DUF423; COGs: COG2363 Uncharacterized small membrane protein; InterPro IPR006696; KEGG: bpf:BpOF4_07255 hypothetical protein; PFAM: protein of unknown function DUF423; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF423). (167 aa)    
Predicted Functional Partners:
Isop_2273
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR018109: IPR001645: IPR013221: IPR004101; KEGG: sti:Sthe_3030 FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
       0.455
Isop_3695
COGs: COG1277 ABC-type transport system involved in multi-copper enzyme maturation permease component; InterPro IPR019196; KEGG: cts:Ctha_0317 putative permease of ABC transporter; PFAM: ABC-type uncharacterised transport system; SPTR: Putative permease of ABC transporter; PFAM: ABC-type uncharacterized transport system.
 
     0.405
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.