STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2285COGs: COG1657 Squalene cyclase; InterPro IPR006400: IPR018333: IPR001330; KEGG: psl:Psta_1738 squalene-hopene cyclase; PFAM: Prenyltransferase/squalene oxidase; PRIAM: Squalene--hopene cyclase; SPTR: Squalene-hopene cyclase; TIGRFAM: squalene-hopene cyclase; squalene/oxidosqualene cyclase; PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase. (661 aa)    
Predicted Functional Partners:
Isop_2284
Hopanoid biosynthesis associated radical SAM protein HpnH; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR017833: IPR007197; KEGG: ppd:Ppro_1192 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM superfamily; Domain of unknown function (DUF3463); TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH.
 
   
 0.905
Isop_2195
Prenyltransferase/squalene oxidase; InterPro IPR001917: IPR001330; KEGG: plm:Plim_4048 cycloartenol synthase-like protein; PFAM: Prenyltransferase/squalene oxidase; SPTR: Putative uncharacterized protein.
     
  0.900
Isop_1955
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: neu:NE1170 putative dihydroflavonol-4-reductase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: hopanoid-associated sugar epimerase.
 
   0.766
Isop_3497
Squalene-associated FAD-dependent desaturase; COGs: COG3349 conserved hypothetical protein; InterPro IPR017830: IPR002937: IPR001613; KEGG: plm:Plim_3204 squalene-associated FAD-dependent desaturase; PFAM: amine oxidase; SPTR: Carotene 7,8-desaturase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: Flavin containing amine oxidoreductase; TIGRFAM: squalene-associated FAD-dependent desaturase.
 
   
 0.701
Isop_2283
COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845; KEGG: psl:Psta_1736 purine or other phosphorylase family 1; PFAM: purine or other phosphorylase family 1; SPTR: Purine or other phosphorylase family 1; PFAM: Phosphorylase superfamily.
 
   
 0.580
Isop_0989
COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: rrs:RoseRS_0386 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, family 2; PFAM: Glycosyl transferase family 2.
 
     0.536
Isop_1743
Ceramide glucosyltransferase; COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; KEGG: tye:THEYE_A1783 ceramide glucosyltransferase, putative; PRIAM: Ceramide glucosyltransferase; SPTR: Ceramide glucosyltransferase, putative; TIGRFAM: hopanoid biosynthesis associated glycosyl transferase protein HpnI.
 
     0.533
Isop_3499
Squalene synthase HpnC; COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR017827: IPR002060; KEGG: plm:Plim_2245 squalene synthase HpnC; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Phytoene synthase-related protein; TIGRFAM: squalene synthase HpnC; PFAM: Squalene/phytoene synthase; TIGRFAM: squalene synthase HpnC.
 
  
 0.518
Isop_3498
COGs: COG1562 Phytoene/squalene synthetase; InterPro IPR002060: IPR019845; KEGG: sus:Acid_1266 farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase; PRIAM: Phytoene synthase; SPTR: Farnesyl-diphosphate farnesyltransferase; PFAM: Squalene/phytoene synthase.
 
  
 0.487
Isop_0015
Hypothetical protein; KEGG: mno:Mnod_6296 glycosyl transferase family 2; SPTR: Glycosyl transferase family 2.
  
     0.468
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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