Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2347Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: plm:Plim_2239 protein of unknown function DUF58; PFAM: protein of unknown function DUF58; SPTR: Probable membrane protein; PFAM: Protein of unknown function DUF58. (499 aa)    
Predicted Functional Partners:
Isop_2348
COGs: COG1305 Transglutaminase-like protein; InterPro IPR002931; KEGG: plm:Plim_2238 transglutaminase domain protein; PFAM: transglutaminase domain-containing protein; SMART: transglutaminase domain-containing protein; SPTR: Transglutaminase domain protein; PFAM: Transglutaminase-like superfamily.
 
    0.902
Isop_2349
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR003593: IPR016366: IPR011703; KEGG: psl:Psta_3996 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: ATPase associated with various cellular activities AAA_3; PFAM: ATPase family associated with various cellular activities (AAA).
 
    0.678
Isop_0465
Hypothetical protein; KEGG: rba:RB13032 putative permease; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
 
    0.635
Isop_0695
COGs: COG1305 Transglutaminase-like protein; InterPro IPR002931; KEGG: plm:Plim_1293 transglutaminase domain protein; PFAM: transglutaminase domain-containing protein; SMART: transglutaminase domain-containing protein; SPTR: Transglutaminase domain protein; PFAM: Transglutaminase-like superfamily; Domain of unknown function (DUF3488).
 
    0.610
Isop_0071
KEGG: psl:Psta_1977 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.505
Isop_2201
KEGG: rba:RB6430 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.468
Isop_2515
Hypothetical protein; KEGG: hsa:4583 mucin 2, oligomeric mucus/gel-forming; SPTR: Mucin-2.
  
     0.460
Isop_2915
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterProIPR019782: IPR017986: IPR009056: IPR001680: IPR 019775: IPR019781; KEGG: rrs:RoseRS_4025 NB-ARC domain-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: WD-40 repeat protein; PFAM: WD domain, G-beta repeat; Planctomycete cytochrome C.
  
     0.411
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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