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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2379Redoxin domain protein; InterPro IPR017937: IPR013740: IPR000866: IPR017936; KEGG: ote:Oter_0137 redoxin domain-containing protein; PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: AhpC/TSA family. (392 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 0.698
Isop_0047
Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR017936; KEGG: plm:Plim_0535 cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: Cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome C biogenesis protein transmembrane region; Protein of unknown function, DUF255.
 
 
 0.687
Isop_3158
Cyclic nucleotide-binding protein; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR017900: IPR018528: IPR018488: IPR002373: IPR 000595: IPR001041: IPR017896; KEGG: sus:Acid_4310 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ferredoxin; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
 
 0.581
Isop_0020
COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR000103: IPR013027: IPR008255; KEGG: acp:A2cp1_4094 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
 
 
 0.577
Isop_2670
NAD-dependent formate dehydrogenase flavoprotein subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: mno:Mnod_8359 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F [...]
  
   0.543
Isop_3157
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR001949: IPR002023: IPR011538: IPR019554: IPR 019575; KEGG: kfl:Kfla_2118 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase- [...]
  
   0.543
msrB
methionine-R-sulfoxide reductase; COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide methionine sulfoxide reductase msrB; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase.
  
 0.473
Isop_0635
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0348 Polyferredoxin; InterPro IPR017896: IPR017900; KEGG: hoh:Hoch_0561 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain.
  
 
 0.467
Isop_3584
Cytochrome c assembly protein; COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR002541; KEGG: bba:Bd1606 cytochrome c-type biogenesis protein; PFAM: cytochrome c assembly protein; SPTR: Cytochrome C assembly protein; PFAM: Cytochrome C assembly protein.
  
  
 0.464
Isop_2700
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763: IPR013027: IPR004099; KEGG: psl:Psta_1619 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Rhodanese-like domain; Pyridine nucleotide-disul [...]
  
 
 0.445
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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