STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2401Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: plm:Plim_1026 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family. (182 aa)    
Predicted Functional Partners:
cobS
Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.959
Isop_2403
Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
  
 0.954
Isop_1334
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: psl:Psta_4229 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family.
  
     0.647
Isop_3350
CobB/CobQ domain protein glutamine amidotransferase; COGs: COG1797 Cobyrinic acid a c-diamide synthase; InterPro IPR017929: IPR011698; KEGG: psl:Psta_3042 CobB/CobQ domain protein glutamine amidotransferase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: CobB/CobQ domain protein glutamine amidotransferase; PFAM: CobB/CobQ-like glutamine amidotransferase domain.
 
  
 0.570
Isop_2297
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: stp:Strop_3355 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family.
  
     0.557
Isop_2405
ABC transporter substrate-binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: rba:RB11981 ABC transporter substrate-binding protein; SPTR: Probable ABC transporter (Substrate-binding protein); PFAM: Periplasmic binding protein.
     
 0.510
Isop_3631
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterProIPR012818: IPR014008: IPR006342: IPR006365: IPR 000878: IPR007848; KEGG: psl:Psta_2973 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; methyltransferase small; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subun [...]
 
  
 0.503
Isop_2404
Protein of unknown function DUF71 ATP-binding region; COGs: COG2102 ATPase of PP-loop superfamily; InterPro IPR002761; KEGG: aba:Acid345_3648 protein of unknown function DUF71, ATPase; PFAM: protein of unknown function DUF71 ATP-binding region; SPTR: Putative uncharacterized protein; PFAM: ATP-binding region; TIGRFAM: MJ0570-related uncharacterized domain.
       0.481
Isop_2406
KEGG: plm:Plim_1022 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.460
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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