STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2434KEGG: dsa:Desal_2132 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Mu-like prophage major head subunit gpT. (687 aa)    
Predicted Functional Partners:
Isop_2435
Phage portal protein, lambda family; COGs: COG5511 Bacteriophage capsid protein; InterPro IPR006429; KEGG: lhk:LHK_01658 phage portal protein, lambda family; PFAM: portal protein lambda; SPTR: Phage portal protein, lambda family; TIGRFAM: phage portal protein, lambda family; PFAM: Phage portal protein, lambda family; TIGRFAM: phage portal protein, lambda family.
 
    0.947
Isop_2433
Protein of unknown function UCP030771; COGs: COG5471 conserved hypothetical protein; InterPro IPR011231; KEGG: sbl:Sbal_3597 gifsy-2 prophage; putative RecA/RadA recombinase; PFAM: protein of unknown function UCP030771; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2190).
 
    0.935
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
 0.884
Isop_2425
KEGG: sit:TM1040_1281 hypothetical protein; SPTR: Putative uncharacterized protein.
 
    0.824
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 
 0.800
Isop_2436
KEGG: osa:4346641 hypothetical protein; SPTR: Putative Peptidyl Prolyl cis-trans isomerase.
       0.773
Isop_2452
KEGG: plm:Plim_2131 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Phage terminase large subunit (GpA).
  
     0.696
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
   
 
 0.694
Isop_0962
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593: IPR001943: IPR004176: IPR003959: IPR 013093: IPR019489: IPR001270: IPR018368; KEGG: plm:Plim_0603 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA-2 domain protein; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA [...]
   
 
 0.694
Isop_2430
KEGG: avi:Avi_8200 replication protein B; SPTR: Replication protein B.
       0.671
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.