STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2445ParB domain protein nuclease; COGs: COG0863 DNA modification methylase; InterPro IPR003115: IPR002941: IPR002295: IPR015840; KEGG: cbe:Cbei_1632 DNA methylase N-4/N-6 domain-containing protein; PFAM: ParB domain protein nuclease; DNA methylase N-4/N-6 domain protein; SMART: ParB domain protein nuclease; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase; ParB-like nuclease domain. (446 aa)    
Predicted Functional Partners:
Isop_2435
Phage portal protein, lambda family; COGs: COG5511 Bacteriophage capsid protein; InterPro IPR006429; KEGG: lhk:LHK_01658 phage portal protein, lambda family; PFAM: portal protein lambda; SPTR: Phage portal protein, lambda family; TIGRFAM: phage portal protein, lambda family; PFAM: Phage portal protein, lambda family; TIGRFAM: phage portal protein, lambda family.
 
    0.776
Isop_2446
KEGG: rlt:Rleg2_1131 hypothetical protein; SPTR: ORF87.
       0.773
Isop_2447
KEGG: btr:Btr_0991 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Isop_2448
Domain of unknown function DUF1937; InterPro IPR015235; KEGG: pag:PLES_39201 hypothetical protein; PFAM: Domain of unknown function DUF1937; SPTR: Putative uncharacterized protein; PFAM: Nucleoside 2-deoxyribosyltransferase; Domain of unknown function (DUF1937).
       0.773
Isop_2455
Resolvase domain protein; COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119: IPR011109; KEGG: hoh:Hoch_2866 resolvase domain protein; PFAM: Resolvase domain; Recombinase; SPTR: Resolvase domain protein; PFAM: Recombinase; Resolvase, N terminal domain.
 
     0.765
Isop_2410
Resolvase domain protein; COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR007087: IPR006119: IPR011109; KEGG: mag:amb1201 site-specific recombinase; PFAM: Resolvase domain; Recombinase; SPTR: Site-specific recombinase; PFAM: Recombinase; Resolvase, N terminal domain.
 
     0.760
Isop_2454
KEGG: tai:Taci_1503 putative bacteriophage related protein; SPTR: Putative bacteriophage related protein; PFAM: Protein of unknown function (DUF2924).
 
     0.754
Isop_2425
KEGG: sit:TM1040_1281 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.750
Isop_2443
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterProIPR014021: IPR001650: IPR006935: IPR018886: IPR 014001; KEGG: mag:amb0356 superfamily II DNA/RNA helicase; PFAM: type III restriction protein res subunit; helicase domain protein; Uncharacterised protein family UPF0547; SMART: helicase domain protein; DEAD-like helicase; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; Uncharacterised protein family UPF0547.
 
     0.626
Isop_2433
Protein of unknown function UCP030771; COGs: COG5471 conserved hypothetical protein; InterPro IPR011231; KEGG: sbl:Sbal_3597 gifsy-2 prophage; putative RecA/RadA recombinase; PFAM: protein of unknown function UCP030771; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2190).
 
     0.617
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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