Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
Isop_2461RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627: IPR013249: IPR014284; KEGG: plm:Plim_2616 RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase sigma factor, sigma-70 family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)    
Predicted Functional Partners:
Isop_0287
Amidohydrolase 2; COGs: COG1904 Glucuronate isomerase; KEGG: plm:Plim_2160 amidohydrolase 2; SPTR: Putative uncharacterized protein; PFAM: Glucuronate isomerase.
  
     0.712
Isop_0849
KEGG: psl:Psta_2453 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.690
Isop_2618
InterPro IPR003400; KEGG: plm:Plim_3761 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR.
  
    0.683
Isop_0202
KEGG: plm:Plim_3249 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.672
Isop_1364
Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: rba:RB12167 hypothetical protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Putative uncharacterized protein.
  
     0.653
Isop_2201
KEGG: rba:RB6430 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.642
Isop_0409
Prenyltransferase/squalene oxidase; InterPro IPR001330; KEGG: plm:Plim_0306 A-macroglobulin complement component; PFAM: Prenyltransferase/squalene oxidase; SPTR: A-macroglobulin complement component.
  
     0.636
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.616
Isop_3405
KEGG: rba:RB10483 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3467).
  
     0.614
Isop_2987
KEGG: psl:Psta_3111 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.600
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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