STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2469COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR006108; KEGG: afw:Anae109_2134 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. (313 aa)    
Predicted Functional Partners:
Isop_2748
COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR020615: IPR020610: IPR001412: IPR020613: IPR 020616: IPR020617: IPR002155; KEGG: gau:GAU_1289 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
 0.999
Isop_1169
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: acp:A2cp1_2280 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: 3-hydroxybutyryl-CoA dehydratase; PFAM: Enoyl-CoA hydratase/isomerase family.
 0.998
Isop_1788
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR018376: IPR001753; KEGG: msv:Mesil_1247 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
 0.958
Isop_1449
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090; KEGG: gur:Gura_2352 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 0.935
Isop_3707
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006089: IPR006092: IPR006091: IPR006090; KEGG: psl:Psta_3650 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 
 0.934
Isop_0657
COGs: COG1960 Acyl-CoA dehydrogenase; KEGG: psl:Psta_0990 putative isovaleryl-CoA dehydrogenase protein; SPTR: Putative isovaleryl-CoA dehydrogenase protein.
  
 0.753
Isop_2468
Hypothetical protein; KEGG: cre:CHLREDRAFT_147815 flagellar associated protein; SPTR: Polysaccharide deacetylase.
       0.518
Isop_1582
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006158: IPR006098: IPR006159: IPR006099; KEGG: mxa:MXAN_2263 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase, alpha subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain.
     
 0.514
Isop_1583
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099; KEGG: rru:Rru_A2480 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase, heterodimeric type, beta chain.
     
 0.514
Isop_2470
KEGG: nhl:Nhal_2099 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.482
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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