STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2478Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: plm:Plim_0907 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme. (378 aa)    
Predicted Functional Partners:
Isop_2477
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR000683: IPR006311; KEGG: plm:Plim_0037 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
 
     0.786
Isop_1845
Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: psl:Psta_4609 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme.
  
     0.700
Isop_0462
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR006311; KEGG: plm:Plim_1207 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Probable dehydrogenase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.695
Isop_1252
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR006311: IPR000683; KEGG: plm:Plim_0111 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
 
     0.630
Isop_2479
ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
 
     0.619
Isop_2678
Heme-binding protein; InterPro IPR009056: IPR013427; KEGG: plm:Plim_2734 membrane-bound dehydrogenase domain protein; SPTR: Heme-binding protein; TIGRFAM: heme-binding protein; PFAM: Cytochrome c; TIGRFAM: putative heme-binding domain, Pirellula/Verrucomicrobium type.
  
     0.500
Isop_3678
InterPro IPR010496; KEGG: dfe:Dfer_0069 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
    0.464
Isop_1244
Xylose isomerase domain-containing protein TIM barrel; COGs: COG3622 Hydroxypyruvate isomerase; InterPro IPR006311: IPR012307; KEGG: zpr:ZPR_4222 probable glyoxylate-induced protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Probable glyoxylate-induced protein; PFAM: Xylose isomerase-like TIM barrel; Belongs to the hyi family.
  
     0.448
Isop_1912
Membrane-bound dehydrogenase domain protein; InterPro IPR003088: IPR013428: IPR013427: IPR009056; KEGG: plm:Plim_0902 heme-binding protein; PFAM: cytochrome c class I; SPTR: Heme-binding protein; TIGRFAM: membrane-bound dehydrogenase domain protein; heme-binding protein; PFAM: Cytochrome c; TIGRFAM: putative membrane-bound dehydrogenase domain; putative heme-binding domain, Pirellula/Verrucomicrobium type.
  
     0.439
Isop_3656
Protein of unknown function DUF1080; InterPro IPR010496; KEGG: psl:Psta_2956 membrane-bound dehydrogenase domain protein; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.419
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.