Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2488Protein of unknown function DUF1446; InterPro IPR010839; KEGG: sus:Acid_3874 hypothetical protein; PFAM: protein of unknown function DUF1446; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1446). (479 aa)    
Predicted Functional Partners:
Isop_2489
KEGG: rpf:Rpic12D_0110 protein of unknown function DUF1446; SPTR: Putative uncharacterized protein.
 
  
 0.905
Isop_2487
Hypothetical protein; KEGG: cef:CE1458 PTS glucose-specific IIABC; SPTR: PTS glucose-specific IIABC.
       0.551
Isop_1527
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR011762: IPR011763: IPR000022; KEGG: psl:Psta_0088 propionyl-CoA carboxylase; PFAM: carboxyl transferase; PRIAM: Methylcrotonoyl-CoA carboxylase; SPTR: Propionyl-CoA carboxylase; PFAM: Carboxyl transferase domain.
  
  
 0.548
Isop_1588
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR011762: IPR011763: IPR000438: IPR000022; KEGG: sus:Acid_6960 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Carboxyl transferase; PFAM: Carboxyl transferase domain.
  
  
 0.548
Isop_0527
Short-chain dehydrogenase/reductase SDR; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198: IPR002347; KEGG: psl:Psta_0898 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Oxidoreductase, short-chain dehydrogenase/reductase family protein; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.419
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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