STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_2489KEGG: rpf:Rpic12D_0110 protein of unknown function DUF1446; SPTR: Putative uncharacterized protein. (118 aa)    
Predicted Functional Partners:
Isop_2748
COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR020615: IPR020610: IPR001412: IPR020613: IPR 020616: IPR020617: IPR002155; KEGG: gau:GAU_1289 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.935
Isop_2488
Protein of unknown function DUF1446; InterPro IPR010839; KEGG: sus:Acid_3874 hypothetical protein; PFAM: protein of unknown function DUF1446; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1446).
 
  
 0.905
Isop_0911
GAF sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018: IPR003661: IPR003594: IPR001789: IPR 005467: IPR004358; KEGG: tcx:Tcr_2068 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; response regulator receiver; SPTR: Sensory transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, D [...]
   
 0.746
Isop_3271
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003661: IPR 003594: IPR001789: IPR005467: IPR000700: IPR008207: IPR013767; KEGG: psl:Psta_1412 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid h [...]
   
 0.746
Isop_0220
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 004358: IPR013655: IPR003661: IPR003594: IPR001610; KEGG: dma:DMR_33580 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver; SPTR: Two-compo [...]
   
 0.726
Isop_1037
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR001610: IPR003661: IPR003594: IPR 001789: IPR005467: IPR013767: IPR013656: IPR004358; KEGG: cyb:CYB_1640 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regul [...]
   
 0.726
Isop_2913
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 004358: IPR001610: IPR003661: IPR003594: IPR013656: IPR013655; KEGG: rxy:Rxyl_2663 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Multi-sensor hyb [...]
   
 0.726
Isop_2980
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR004358: IPR 003661: IPR003594: IPR013767; KEGG: psl:Psta_1412 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein [...]
   
 0.726
Isop_0320
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013656: IPR003661: IPR003594: IPR 001789: IPR000014: IPR004358: IPR005467: IPR000700; KEGG: nde:NIDE1908 putative sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensory transduction histidine kinase; TIGRFAM: PAS sensor prot [...]
   
 0.720
Isop_0944
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR003661: IPR003594: IPR001789: IPR 005467: IPR000700: IPR013767: IPR004358; KEGG: rba:RB13181 sensory transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiv [...]
   
 0.720
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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