Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2522Hypothetical protein; KEGG: met:M446_0109 response regulator receiver protein; SPTR: Two component sensor kinase/response regulator hybrid. (211 aa)    
Predicted Functional Partners:
Isop_2523
WD40 repeat, subgroup; COGs: COG2319 FOG: WD40 repeat; InterProIPR019782: IPR017986: IPR009056: IPR019775: IPR 019781: IPR001680; KEGG: sus:Acid_5711 hypothetical protein; PFAM: WD40 repeat, subgroup; SPTR: WD-40 repeat protein; PFAM: WD domain, G-beta repeat; Planctomycete cytochrome C.
       0.773
Isop_2521
Type I phosphodiesterase/nucleotide pyrophosphatase; COGs: COG1524 Uncharacterized protein of the AP superfamily; InterPro IPR002591; KEGG: azl:AZL_b05760 hypothetical protein; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Putative uncharacterized protein; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
       0.732
Isop_2524
Protein of unknown function DUF1549; InterPro IPR003343: IPR011444; KEGG: sus:Acid_5709 hypothetical protein; PFAM: protein of unknown function DUF1549; Ig domain protein group 2 domain protein; SPTR: Putative uncharacterized protein; PFAM: Bacterial Ig-like domain (group 2); Protein of unknown function (DUF1549); Protein of unknown function (DUF1553).
       0.528
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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