STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_2529COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143; KEGG: plm:Plim_2597 biotin/lipoate A/B protein ligase; PFAM: biotin/lipoate A/B protein ligase; SPTR: Biotin/lipoate A/B protein ligase; PFAM: Biotin/lipoate A/B protein ligase family. (309 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 
 0.929
Isop_1354
COGs: COG0321 Lipoate-protein ligase B; InterPro IPR004143; KEGG: plm:Plim_3383 lipoate-protein ligase B-like protein; PFAM: biotin/lipoate A/B protein ligase; SPTR: Lipoate-protein ligase B; TIGRFAM: lipoate-protein ligase B.
   
 0.914
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.836
Isop_0329
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030: IPR014031; KEGG: aae:aq_1717 3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: Beta-ketoacyl synthase; SPTR: 3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.800
Isop_0517
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
  0.800
Isop_0518
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030: IPR014031; KEGG: plm:Plim_2562 beta-ketoacyl synthase; PFAM: Beta-ketoacyl synthase; SPTR: 3-oxoacyl-(Acyl carrier protein) synthase; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.800
Isop_0947
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
  0.800
Isop_1126
Beta-ketoacyl synthase; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030: IPR014031; KEGG: tro:trd_A0447 beta-ketoacyl-acyl-carrier-protein synthase II; PFAM: Beta-ketoacyl synthase; SPTR: Putative uncharacterized protein; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.800
Isop_1237
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
  0.800
Isop_1238
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
     
  0.800
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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