Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2559Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: sus:Acid_6183 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase. (642 aa)    
Predicted Functional Partners:
Isop_1556
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR002052: IPR008265: IPR001087: IPR000917; KEGG: psl:Psta_3960 sulfatase; PFAM: sulfatase; lipolytic protein G-D-S-L family; SPTR: Choline sulfatase; PFAM: GDSL-like Lipase/Acylhydrolase; Sulfatase.
  
     0.774
Isop_2942
Sulfatase; COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: psl:Psta_4602 sulfatase; PFAM: sulfatase; SPTR: Heparan N-sulfatase; PFAM: Sulfatase.
  
     0.771
Isop_3638
Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: sli:Slin_1433 protein of unknown function DUF323; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme.
  
 
   0.536
Isop_2560
KEGG: cbr:CBG23595 Hypothetical protein CBG23595; SPTR: Phf21b protein.
       0.523
Isop_0290
COGs: COG3379 conserved hypothetical protein; InterPro IPR001917: IPR002591; KEGG: hoh:Hoch_2285 type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
  
     0.481
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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