STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2634Hypothetical protein; COGs: COG1850 Ribulose 1 5-bisphosphate carboxylase large subunit; KEGG: dac:Daci_5642 ribulose-bisphosphate carboxylase; SPTR: Ribulose-bisphosphate carboxylase; PFAM: Ribulose bisphosphate carboxylase large chain, catalytic domain. (475 aa)    
Predicted Functional Partners:
Isop_2228
Hypothetical protein; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: mxa:MXAN_3783 hexapaptide repeat-containing transferase; SPTR: Transferase hexapeptide repeat family protein.
    
 
 0.775
Isop_1633
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: plm:Plim_1747 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain.
  
  
 0.557
Isop_2248
COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR017937: IPR006662: IPR013766: IPR017936; KEGG: psl:Psta_1606 thioredoxin domain protein; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin domain protein; PFAM: Thioredoxin; TIGRFAM: thioredoxin.
  
 
 
 0.490
Isop_2635
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: adg:Adeg_1011 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain.
       0.483
Isop_2636
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR010822: IPR003594: IPR001932; KEGG: cli:Clim_1832 putative PAS/PAC sensor protein; PFAM: Stage II sporulation protein E; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Putative PAS/PAC sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Stage II sporulation protein E (SpoIIE).
       0.483
Isop_0668
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.477
mtnA
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
  
  
 0.470
Isop_0459
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR013766: IPR017937: IPR005746: IPR006662: IPR 017936; KEGG: tal:Thal_1357 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
 
 
 0.438
Isop_3311
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR004620: IPR003171; KEGG: pca:Pcar_1732 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; PRIAM: Methylenetetrahydrofolate reductase (NAD(P)H); SPTR: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form; Belongs to the methylenetetrahydrofolate reductase family.
   
    0.416
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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