STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_2640Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: psl:Psta_2761 transcriptional regulator, BadM/Rrf2 family; PFAM: protein of unknown function UPF0074; SPTR: Putative uncharacterized protein; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator). (164 aa)    
Predicted Functional Partners:
Isop_0815
Cysteine desulfurase IscS; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192: IPR016454; KEGG: cre:CHLREDRAFT_191269 cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; PFAM: Aminotransferase class-V.
  
  
 0.661
Isop_2132
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: rmr:Rmar_1215 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
  
  
 0.661
Isop_0837
Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: psl:Psta_0335 transcriptional regulator, BadM/Rrf2 family; PFAM: protein of unknown function UPF0074; SPTR: Transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator).
  
     0.651
Isop_1969
Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: plm:Plim_1321 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family.
  
  
 0.577
Isop_2321
InterPro IPR000090; KEGG: aeh:Mlg_0710 flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein fliG; PFAM: FliG C-terminal domain.
    
   0.430
Isop_2639
NAD-dependent epimerase/dehydratase; COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR001412: IPR001509; KEGG: gvi:glr3121 methionine adenosyltransferase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Glr3121 protein; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase.
       0.407
Isop_3158
Cyclic nucleotide-binding protein; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR017900: IPR018528: IPR018488: IPR002373: IPR 000595: IPR001041: IPR017896; KEGG: sus:Acid_4310 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ferredoxin; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
  
 0.401
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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