STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_2661Glycoside hydrolase 15-related protein; COGs: COG3387 Glucoamylase and related glycosyl hydrolase; InterPro IPR011613; KEGG: scl:sce1562 glycosyl hydrolase; PFAM: glycoside hydrolase 15-related; SPTR: Glycoside hydrolase 15-related protein; PFAM: Glycosyl hydrolases family 15. (599 aa)    
Predicted Functional Partners:
Isop_1029
COGs: COG3280 Maltooligosyl trehalose synthase; InterPro IPR006589: IPR012767: IPR004300: IPR006047; KEGG: cag:Cagg_2094 maltooligosyl trehalose synthase; PFAM: alpha amylase catalytic region; glycoside hydrolase family 57; SMART: alpha amylase catalytic sub domain; SPTR: Malto-oligosyltrehalose synthase; TIGRFAM: malto-oligosyltrehalose synthase; PFAM: Alpha amylase, catalytic domain; Glycosyl hydrolase family 57; Domain of unknown function (DUF3536); TIGRFAM: malto-oligosyltrehalose synthase.
 
  
 0.596
nhaA
Sodium/proton antiporter, NhaA family; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
       0.532
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.431
glgE
Glycosyl transferase group 1; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
 
   
 0.426
Isop_1028
Maltooligosyl trehalose hydrolase; COGs: COG0296 1 4-alpha-glucan branching enzyme; InterPro IPR006589: IPR012768: IPR004193: IPR006047; KEGG: cyb:CYB_2529 malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: Malto-oligosyltrehalose trehalohydrolase; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: Alpha amylase, catalytic domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); TIGRFAM: malto-oligosyltrehalose trehalohydrolase.
 
  
 0.418
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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