Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2681Endonuclease/exonuclease/phosphatase; InterPro IPR005135; KEGG: sal:Sala_1018 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/Exonuclease/phosphatase family. (271 aa)    
Predicted Functional Partners:
Isop_2680
Hypothetical protein; KEGG: rme:Rmet_5987 negative regulation of plasmid gene expression transcriptional repressor activity; SPTR: Negative regulation of plasmid gene expression transcriptional repressor activity.
       0.773
Isop_2866
Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: rrs:RoseRS_1377 aminotransferase, class V; PFAM: aminotransferase class V; SPTR: Aminotransferase, class V; PFAM: Aminotransferase class-V.
  
 
   0.550
Isop_1377
Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: sti:Sthe_0800 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Similar to selenocysteine lyase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein.
    
   0.480
Isop_1794
Aminotransferase class V; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192; KEGG: psl:Psta_3767 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
    
   0.480
Isop_1968
COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: ace:Acel_1138 SufS subfamily cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Cysteine desulfurases, SufS subfamily; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily.
    
   0.480
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.