Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2682Na-Ca exchanger/integrin-beta4; COGs: COG2340 Uncharacterized protein with SCP/PR1 domains; InterPro IPR014044: IPR003644; KEGG: dal:Dalk_4321 hypothetical protein; PFAM: Na-Ca exchanger/integrin-beta4; SCP-like extracellular; SMART: Na-Ca exchanger/integrin-beta4; SPTR: SCP-like extracellular protein, putative; PFAM: Cysteine-rich secretory protein family; Calx-beta domain. (640 aa)    
Predicted Functional Partners:
Isop_2044
Hypothetical protein; InterPro IPR013424; KEGG: rba:RB4575 signal peptide; SPTR: Putative uncharacterized protein.
   
    0.473
Isop_2375
Dockerin type 1; InterPro IPR018247: IPR018242; KEGG: aba:Acid345_4018 integrin-like protein; PFAM: Dockerin type 1; SPTR: Integrin-like protein; PFAM: Dockerin type I repeat.
   
    0.473
Isop_2363
Protein of unknown function DUF820; InterPro IPR008538; KEGG: mar:MAE_05220 hypothetical protein; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.418
Isop_2364
InterPro IPR008538; KEGG: cyh:Cyan8802_0022 protein of unknown function DUF820; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.409
Isop_2365
Protein of unknown function DUF820; InterPro IPR008538; KEGG: mar:MAE_05220 hypothetical protein; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.409
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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