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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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Isop_2714RNA procession exonuclease-like protein; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; KEGG: rrs:RoseRS_1582 RNA procession exonuclease-like protein; SPTR: Exonuclease of the beta-lactamase fold involved in RNA processing-like protein; PFAM: Metallo-beta-lactamase superfamily. (401 aa)    
Predicted Functional Partners:
Isop_2715
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR016059: IPR012309; KEGG: rrs:RoseRS_1583 ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region.
 
 0.987
Isop_3434
Metallophosphoesterase; InterPro IPR004843; KEGG: psl:Psta_1609 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase.
    
 0.850
Isop_3577
Hypothetical protein; COGs: COG1407 ICC-like phosphoesterase; KEGG: pfu:PF1484 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: putative phosphoesterase, SbcD/Mre11-related.
 
     0.780
Isop_3155
COGs: COG3424 naringenin-chalcone synthase; InterPro IPR011141: IPR001099: IPR012328; KEGG: syw:SYNW0993 putative chalcone synthase; PFAM: chalcone and stilbene synthase domain protein; PRIAM: Naringenin-chalcone synthase; SPTR: Chalcone synthase (CHS); PFAM: Chalcone and stilbene synthases, N-terminal domain; Chalcone and stilbene synthases, C-terminal domain.
  
 
 0.761
Isop_0720
COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: plm:Plim_1587 RNP-1 like RNA-binding protein; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; SPTR: RNP-1 like RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain).
   
 0.741
Isop_2358
COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: plm:Plim_1587 RNP-1 like RNA-binding protein; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; SPTR: RNP-1 like RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain).
   
 0.741
Isop_0698
DEAD/DEAH box helicase domain protein; COGs: COG1201 Lhr-like helicase; InterProIPR011545: IPR001650: IPR013701: IPR014001: IPR 014021: IPR017170; KEGG: tga:TGAM_0576 ATP-dependent helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: ATP-dependent helicase, lhr-like protein (Lhr); PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase.
 
    0.733
Isop_1922
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR001098: IPR002421: IPR 008918: IPR002298: IPR018320: IPR019760; KEGG: plm:Plim_3011 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; SMART: DNA-directed DNA polymerase; 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polym [...]
  
 0.674
Isop_1517
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021: IPR001650: IPR014014: IPR000629: IPR 014001: IPR011545; KEGG: psl:Psta_1620 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: DEAD/DEAH box helicase domain protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
 0.667
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.610
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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