Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Isop_2717InterPro IPR013096; KEGG: tcu:Tcur_1342 cupin 2 conserved barrel domain protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Cupin 2 conserved barrel domain protein; PFAM: Cupin domain. (123 aa)    
Predicted Functional Partners:
Isop_2716
Hypothetical protein.
       0.433
Isop_3417
COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR006070: IPR017867: IPR000106; KEGG: plm:Plim_2592 protein-tyrosine phosphatase, low molecular weight; PFAM: Protein-tyrosine phosphatase, low molecular weight; SUA5/yciO/yrdC domain; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein-tyrosine phosphatase, low molecular weight; PFAM: Low molecular weight phosphotyrosine protein phosphatase; yrdC domain; Belongs to the SUA5 family.
  
    0.406
Isop_2718
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
       0.405
Isop_0923
COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: cyb:CYB_1783 sugar transferase family protein; PFAM: sugar transferase; SPTR: Bacterial sugar transferase family protein; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.
  
  
 0.401
Isop_3192
COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: gme:Gmet_2031 sugar transferase; PFAM: sugar transferase; SPTR: Sugar transferase, PEP-CTERM system associated; PFAM: Bacterial sugar transferase.
  
  
 0.401
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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