Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2756KEGG: plm:Plim_2088 hypothetical protein; SPTR: Putative uncharacterized protein. (350 aa)    
Predicted Functional Partners:
Isop_2755
Conserved repeat domain protein; InterPro IPR010916: IPR006650: IPR001434; KEGG: psl:Psta_0523 conserved repeat domain protein; SPTR: 60 kDa outer membrane protein; TIGRFAM: conserved repeat domain protein; PFAM: Domain of unknown function DUF11; TIGRFAM: conserved repeat domain.
       0.773
Isop_0887
Peptidoglycan-binding lysin domain protein; InterPro IPR018392: IPR002482; KEGG: dpo:Dpse_GA28568 GA28568 gene product from transcript GA28568-RA; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: GA28568; PFAM: LysM domain.
   
    0.567
Isop_2754
Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR017927: IPR008333: IPR001433: IPR019480: IPR 012165; KEGG: psl:Psta_4647 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; SPTR: Dihydroorotate dehydrogenase electron transfer subunit; PFAM: Oxidoreducta [...]
       0.435
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (26%) [HD]