Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2758Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR017909: IPR013838: IPR000683: IPR006311; KEGG: rba:RB3070 putative oxidoreductase; PFAM: oxidoreductase domain protein; SPTR: Putative uncharacterized protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence. (498 aa)    
Predicted Functional Partners:
Isop_0079
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: plm:Plim_2996 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.699
Isop_0595
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: rca:Rcas_2202 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold.
  
     0.631
Isop_2337
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: psl:Psta_3890 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Probable NADH-dependent dyhydrogenase related protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
     0.628
Isop_3656
Protein of unknown function DUF1080; InterPro IPR010496; KEGG: psl:Psta_2956 membrane-bound dehydrogenase domain protein; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.620
Isop_1476
Protein of unknown function DUF1080; InterPro IPR010496; KEGG: rba:RB569 hypothetical protein; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.600
Isop_0786
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683: IPR004104; KEGG: plm:Plim_2198 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain.
  
     0.584
Isop_0247
InterPro IPR010496; KEGG: rmr:Rmar_1742 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.558
Isop_1220
Protein of unknown function DUF1080; InterPro IPR010496; KEGG: rba:RB9196 secreted glycosyl hydrolase; PFAM: protein of unknown function DUF1080; SPTR: Probable secreted glycosyl hydrolase; PFAM: Domain of Unknown Function (DUF1080).
  
     0.540
Isop_0606
InterPro IPR010496; KEGG: tra:Trad_1254 protein of unknown function DUF1080; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.536
Isop_1907
Protein of unknown function DUF1080; InterPro IPR010496; KEGG: sus:Acid_0701 hypothetical protein; PFAM: protein of unknown function DUF1080; SPTR: Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF1080).
  
     0.520
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.