Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2764Endoribonuclease L-PSP; COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006175; KEGG: rba:RB1270 putative translation initiation inhibitor; PFAM: Endoribonuclease L-PSP; SPTR: Endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. (157 aa)    
Predicted Functional Partners:
Isop_2766
COGs: COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; InterPro IPR006650; KEGG: rca:Rcas_2756 hypothetical protein; SPTR: Uncharacterized protein containing SIS (Sugar isomerase) phosphosugar binding domain-like protein.
       0.780
Isop_2765
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR020904: IPR002198; KEGG: sli:Slin_5818 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
       0.779
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.643
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
 
 0.636
Isop_2867
Alanine racemase domain protein; COGs: COG3616 amino acid aldolase or racemase; InterPro IPR001608; KEGG: psl:Psta_1894 alanine racemase domain protein; PFAM: alanine racemase domain protein; SPTR: D-threonine aldolase, metal-activated pyridoxal enzyme; PFAM: Alanine racemase, N-terminal domain.
 
   
 0.603
pdxJ
Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
     
 0.579
Isop_3461
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG1171 Threonine dehydratase; InterPro IPR001926: IPR000634; KEGG: scl:sce3847 putative serine/threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Putative serine/threonine dehydratase; PFAM: Pyridoxal-phosphate dependent enzyme.
 
 
 0.495
Isop_2763
Hypothetical protein; KEGG: sus:Acid_1421 glycosyl transferase family protein; SPTR: Tetratricopeptide repeat protein.
       0.477
Isop_2762
Hypothetical protein; KEGG: gym:GYMC10_4089 ABC transporter related protein; SPTR: Putative uncharacterized protein M88B7.1f.
       0.458
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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