STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2765Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR020904: IPR002198; KEGG: sli:Slin_5818 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (297 aa)    
Predicted Functional Partners:
Isop_2766
COGs: COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; InterPro IPR006650; KEGG: rca:Rcas_2756 hypothetical protein; SPTR: Uncharacterized protein containing SIS (Sugar isomerase) phosphosugar binding domain-like protein.
 
     0.880
Isop_2764
Endoribonuclease L-PSP; COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006175; KEGG: rba:RB1270 putative translation initiation inhibitor; PFAM: Endoribonuclease L-PSP; SPTR: Endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP.
       0.779
Isop_1507
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198: IPR020904: IPR002347; KEGG: cyb:CYB_0005 short chain dehydrogenase/reductase family oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Oxidoreductase, short chain dehydrogenase/reductase family; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
   0.775
Isop_1434
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR020904: IPR002347; KEGG: mno:Mnod_1178 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
  
     0.774
Isop_2108
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198: IPR002347; KEGG: ade:Adeh_3849 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
   0.755
Isop_1426
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198: IPR020904: IPR002347; KEGG: psl:Psta_3581 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Glucose 1-dehydrogenase-like protein; PFAM: short chain dehydrogenase.
  
 
   0.741
pdxJ
Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
       0.566
Isop_2985
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: sin:YN1551_2013 ankyrin; PFAM: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
    
 0.539
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.521
Isop_2763
Hypothetical protein; KEGG: sus:Acid_1421 glycosyl transferase family protein; SPTR: Tetratricopeptide repeat protein.
       0.477
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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