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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Isop_2814Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR001789: IPR003593: IPR002197; KEGG: mxa:MXAN_0172 sigma-54 dependent DNA-binding response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Sigma-54 dependent DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory protein [...] (458 aa)    
Predicted Functional Partners:
Isop_2815
COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467: IPR003660: IPR004358: IPR003661: IPR 003594: IPR000014; KEGG: ote:Oter_1644 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histidin [...]
 
 
 0.980
Isop_2995
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: psl:Psta_2523 RNA polymerase, sigma 54 subunit, RpoN; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.779
Isop_2816
Magnesium-translocating P-type ATPase; COGs: COG0474 Cation transport ATPase; InterProIPR006415: IPR018303: IPR004014: IPR008250: IPR 005834: IPR006068: IPR001757; KEGG: bwe:BcerKBAB4_3981 magnesium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Magnesium-transporting ATPase, P-type 1; TIGRFAM: magnesium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation tra [...]
       0.547
Isop_2817
MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: bca:BCE_4213 MgtC family protein; PFAM: MgtC/SapB transporter; SPTR: Mg(2+) transport ATPase protein C; PFAM: MgtC family.
       0.514
Isop_1841
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207: IPR004105: IPR003594: IPR002545: IPR 001789: IPR004358: IPR005467; KEGG: aeh:Mlg_0359 CheA signal transduction histidine kinases; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SPTR: CheA signal transduction histidine kin [...]
 
 
 0.491
Isop_2319
Type III secretion system inner membrane P protein; COGs: COG1338 Flagellar biosynthesis pathway component FliP; InterPro IPR005838; KEGG: adg:Adeg_2033 flagellar biosynthetic protein FliP; PFAM: type III secretion system inner membrane P protein; SPTR: Flagellar biosynthetic protein FliP; PFAM: FliP family.
  
  
 0.441
Isop_3271
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003661: IPR 003594: IPR001789: IPR005467: IPR000700: IPR008207: IPR013767; KEGG: psl:Psta_1412 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid h [...]
  
 
 0.418
Isop_1972
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013655: IPR013767: IPR003661: IPR003594: IPR 001789: IPR008207: IPR000014: IPR004358: IPR000896: IPR005467; KEGG: rba:RB159 sensory transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensory transduction histidine k [...]
  
 
 0.401
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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