STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_2816Magnesium-translocating P-type ATPase; COGs: COG0474 Cation transport ATPase; InterProIPR006415: IPR018303: IPR004014: IPR008250: IPR 005834: IPR006068: IPR001757; KEGG: bwe:BcerKBAB4_3981 magnesium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Magnesium-transporting ATPase, P-type 1; TIGRFAM: magnesium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation tra [...] (902 aa)    
Predicted Functional Partners:
Isop_2817
MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: bca:BCE_4213 MgtC family protein; PFAM: MgtC/SapB transporter; SPTR: Mg(2+) transport ATPase protein C; PFAM: MgtC family.
 
 
 0.887
Isop_2554
Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR003148: IPR006037: IPR006153; KEGG: dol:Dole_0855 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; SPTR: Sodium/hydrogen exchanger; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.613
rpsH
SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
    
   0.560
rpsM
SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
   
   0.559
rpsE
SSU ribosomal protein S5P; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
    
   0.558
Isop_2814
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR001789: IPR003593: IPR002197; KEGG: mxa:MXAN_0172 sigma-54 dependent DNA-binding response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Sigma-54 dependent DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory protein [...]
       0.547
Isop_2815
COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467: IPR003660: IPR004358: IPR003661: IPR 003594: IPR000014; KEGG: ote:Oter_1644 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histidin [...]
       0.547
Isop_2419
YD repeat protein; COGs: COG3209 Rhs family protein; InterPro IPR003587: IPR006530: IPR006141; KEGG: plm:Plim_1036 AmoP; PFAM: YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: AmoP; TIGRFAM: YD repeat protein; PFAM: RHS Repeat; Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain; YD repeat (two copies).
   
  
 0.495
rpsO
SSU ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
    
   0.492
rpsB
COGs: COG0052 Ribosomal protein S2; InterPro IPR001865: IPR018130: IPR005706; KEGG: psl:Psta_0952 ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: Ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; Belongs to the universal ribosomal protein uS2 family.
   
   0.491
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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