Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Isop_2817MgtC/SapB transporter; COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: bca:BCE_4213 MgtC family protein; PFAM: MgtC/SapB transporter; SPTR: Mg(2+) transport ATPase protein C; PFAM: MgtC family. (229 aa)    
Predicted Functional Partners:
Isop_2816
Magnesium-translocating P-type ATPase; COGs: COG0474 Cation transport ATPase; InterProIPR006415: IPR018303: IPR004014: IPR008250: IPR 005834: IPR006068: IPR001757; KEGG: bwe:BcerKBAB4_3981 magnesium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Magnesium-transporting ATPase, P-type 1; TIGRFAM: magnesium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation tra [...]
 
 
 0.887
Isop_2317
KEGG: rmr:Rmar_0763 flagellar biosynthetic protein FliR; SPTR: Flagellar biosynthetic protein fliR; PFAM: Bacterial export proteins, family 1.
    
   0.559
Isop_2814
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR001789: IPR003593: IPR002197; KEGG: mxa:MXAN_0172 sigma-54 dependent DNA-binding response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Sigma-54 dependent DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory protein [...]
       0.514
Isop_2815
COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467: IPR003660: IPR004358: IPR003661: IPR 003594: IPR000014; KEGG: ote:Oter_1644 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Integral membrane sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histidin [...]
       0.514
Isop_0276
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757: IPR000695: IPR018303: IPR004014: IPR 008250: IPR005834: IPR006068; KEGG: sat:SYN_00872 calcium-transporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Calcium-transporting ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehal [...]
  
 
 0.480
Isop_2818
Pyruvate phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR000121: IPR002192: IPR008279: IPR010121; KEGG: ddf:DEFDS_0235 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: Pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, [...]
       0.417
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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