STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Isop_2841DEAD/H associated domain protein; COGs: COG1201 Lhr-like helicase; InterProIPR014021: IPR001650: IPR014001: IPR003593: IPR 011545: IPR013701; KEGG: sth:STH886 ATP-dependent DNA helicase; PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; AAA ATPase; helicase domain protein; SPTR: ATP-dependent DNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase. (1575 aa)    
Predicted Functional Partners:
Isop_1352
COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterProIPR000214: IPR012319: IPR000191: IPR015886: IPR 015887; KEGG: slp:Slip_1694 formamidopyrimidine-DNA glycosylase; PFAM: DNA glycosylase/AP lyase, H2TH DNA-binding; Formamidopyrimidine-DNA glycosylase catalytic domain protein; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Putative uncharacterized protein; TIGRFAM: formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg).
  
  
 0.596
Isop_2842
NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: rrs:RoseRS_0359 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family.
       0.483
Isop_2715
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR016059: IPR012309; KEGG: rrs:RoseRS_1583 ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: ATP dependent DNA ligase; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region.
 
    0.445
Isop_3577
Hypothetical protein; COGs: COG1407 ICC-like phosphoesterase; KEGG: pfu:PF1484 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: putative phosphoesterase, SbcD/Mre11-related.
 
    0.437
Isop_1928
Excinuclease ABC C subunit domain protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
   
    0.417
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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