STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_2843Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678: IPR017221; KEGG: plm:Plim_2674 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (386 aa)    
Predicted Functional Partners:
Isop_1084
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839: IPR004838; KEGG: pth:PTH_1314 histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; manually curated; PFAM: Aminotransferase class I and II.
  
  
 0.734
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR004838; KEGG: psl:Psta_4386 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.734
Isop_3037
Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: plm:Plim_0030 protein of unknown function DUF164; PFAM: protein of unknown function DUF164; SPTR: Putative uncharacterized protein; PFAM: Putative zinc ribbon domain.
  
  
 0.677
Isop_2844
Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR018300: IPR001544; KEGG: rxy:Rxyl_0760 aminotransferase, class IV; PFAM: aminotransferase class IV; SPTR: Aminotransferase, class IV; PFAM: Aminotransferase class IV.
  
    0.667
Isop_2845
KEGG: psl:Psta_1684 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.628
Isop_0345
Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: caa:Caka_0677 putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; SPTR: Aminotransferase; PFAM: Aminotransferase class I and II.
   
    0.554
Isop_1450
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR005888: IPR001509; KEGG: msl:Msil_2711 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
    0.526
Isop_2846
COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787: IPR018313; KEGG: cwo:Cwoe_1076 peptidase M29 aminopeptidase II; PFAM: peptidase M29 aminopeptidase II; SPTR: Peptidase M29 aminopeptidase II; PFAM: Thermophilic metalloprotease (M29).
       0.512
Isop_2608
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: plm:Plim_1236 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
 
   
 0.430
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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