STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2847Rhomboid family protein; COGs: COG0705 membrane protein; InterPro IPR013838: IPR002610; KEGG: plm:Plim_1385 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Probable glpG protein; PFAM: Protein of unknown function (DUF3582); Rhomboid family. (311 aa)    
Predicted Functional Partners:
Isop_2846
COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787: IPR018313; KEGG: cwo:Cwoe_1076 peptidase M29 aminopeptidase II; PFAM: peptidase M29 aminopeptidase II; SPTR: Peptidase M29 aminopeptidase II; PFAM: Thermophilic metalloprotease (M29).
       0.516
Isop_2624
COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151: IPR004447; KEGG: psl:Psta_4163 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; PRIAM: C-terminal processing peptidase; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Periplasmic tail-specific proteinase; TIGRFAM: carboxyl-terminal protease; PFAM: C-terminal domain of tail specific protease (DUF3340); Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.
  
     0.474
Isop_0687
InterPro IPR003369; KEGG: plm:Plim_2724 twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: Putative Sec-independent protein translocase component; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family.
   
 
 0.468
tatA
Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
   
 
 0.468
Isop_2623
COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151: IPR004447; KEGG: psl:Psta_4163 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; PRIAM: C-terminal processing peptidase; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Periplasmic tail-specific proteinase; TIGRFAM: carboxyl-terminal protease; PFAM: C-terminal domain of tail specific protease (DUF3340); Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.
  
     0.461
Isop_2833
COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: rxy:Rxyl_1321 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; manually curated; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase.
  
  
 0.433
Isop_2844
Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR018300: IPR001544; KEGG: rxy:Rxyl_0760 aminotransferase, class IV; PFAM: aminotransferase class IV; SPTR: Aminotransferase, class IV; PFAM: Aminotransferase class IV.
       0.426
Isop_2845
KEGG: psl:Psta_1684 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.426
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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