Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Isop_2888Glycosyl hydrolase 38 domain protein; InterPro IPR011682; KEGG: psl:Psta_3607 hypothetical protein; PFAM: glycosyl hydrolase 38 domain protein; SPTR: Putative uncharacterized protein. (1028 aa)    
Predicted Functional Partners:
Isop_2889
Protein of unknown function DUF480; COGs: COG3132 conserved hypothetical protein; InterPro IPR007432; KEGG: psl:Psta_3246 hypothetical protein; PFAM: protein of unknown function DUF480; SPTR: Putative uncharacterized protein; manually curated; PFAM: Protein of unknown function, DUF480; Belongs to the UPF0502 family.
       0.780
Isop_2887
Hypothetical protein; KEGG: mav:MAV_2634 cytochrome P450; SPTR: Putative uncharacterized protein.
       0.516
Isop_1658
COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterPro IPR019734: IPR013026: IPR011260: IPR001440; KEGG: psl:Psta_3991 RNA polymerase alpha subunit domain protein; PFAM: RNA polymerase alpha subunit domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SPTR: RNA polymerase alpha subunit domain protein; PFAM: Tetratricopeptide repeat; Bacterial RNA polymerase, alpha chain C terminal domain.
    
   0.466
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.466
Isop_0502
Galactokinase; COGs: COG0153 Galactokinase; InterProIPR019539: IPR006204: IPR013750: IPR000705: IPR 006203: IPR006206; KEGG: rrs:RoseRS_3819 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily.
   
    0.446
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: alv:Alvin_1646 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
  
    0.442
Isop_1516
MobA-like protein; COGs: COG2068 Uncharacterized MobA-related protein; KEGG: psl:Psta_3801 MobA-like protein; SPTR: Uncharacterized MobA-related protein-like protein; PFAM: Uncharacterized protein family UPF0007.
   
    0.436
Isop_2890
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424: IPR011344; KEGG: amu:Amuc_1863 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
       0.433
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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