Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2894Cadherin; InterPro IPR000601: IPR002126; KEGG: sro:Sros_4284 hypothetical protein; PFAM: Cadherin; SPTR: Putative uncharacterized protein. (559 aa)    
Predicted Functional Partners:
Isop_2160
Secretion protein HlyD family protein; InterPro IPR003997: IPR006143; KEGG: rba:RB10473 alkaline protease secretion protein AprE; PFAM: secretion protein HlyD family protein; SPTR: Similar to alkaline proteinase secretion protein aprE.
  
     0.627
Isop_1399
KEGG: rmr:Rmar_0200 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.591
Isop_2824
Hypothetical protein; InterPro IPR001120: IPR012902; KEGG: plm:Plim_0405 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
  
     0.585
Isop_3063
InterPro IPR011031; KEGG: rba:RB11084 response regulator aspartate phosphatase RapC; SPTR: Putative uncharacterized protein.
  
    0.578
Isop_3151
Peptidase M56 BlaR1; InterPro IPR008756; KEGG: sus:Acid_5553 peptidase M56, BlaR1; PFAM: peptidase M56 BlaR1; SPTR: Peptidase M56, BlaR1.
  
     0.563
Isop_0716
KEGG: rba:RB8980 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1559).
  
     0.558
Isop_3179
Hypothetical protein; KEGG: rba:RB850 signal peptide; SPTR: Putative uncharacterized protein.
  
     0.543
Isop_3075
Forkhead-associated protein; InterPro IPR000253; KEGG: psl:Psta_2714 pyrrolo-quinoline quinone; PFAM: Forkhead-associated protein; SPTR: Putative uncharacterized protein.
  
     0.534
Isop_0706
Protein of unknown function DUF1565; InterPro IPR011506: IPR000209: IPR011459: IPR006626; KEGG: mar:MAE_50880 hypothetical protein; PFAM: protein of unknown function DUF1565; Planctomycete extracellular domain protein; peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Peptidase families S8 and S53 domain protein; PFAM: Protein of unknown function (DUF1565); Subtilase family.
  
 
   0.531
Isop_3546
Hypothetical protein; InterPro IPR002052; KEGG: afv:AFLA_092170 hypothetical protein; SPTR: Minus agglutinin.
  
     0.523
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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