| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Isop_0020 | Isop_1968 | Isop_0020 | Isop_1968 | COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR000103: IPR013027: IPR008255; KEGG: acp:A2cp1_4094 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: ace:Acel_1138 SufS subfamily cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Cysteine desulfurases, SufS subfamily; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily. | 0.917 |
| Isop_0020 | selD | Isop_0020 | Isop_2923 | COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR000103: IPR013027: IPR008255; KEGG: acp:A2cp1_4094 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.913 |
| Isop_0783 | Isop_3475 | Isop_0783 | Isop_3475 | COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896; KEGG: ote:Oter_3934 Fe-S-cluster-containing hydrogenase components 1-like protein; SPTR: Molybdopterin oxidoreductase, iron-sulfur binding subunit. | COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR005225: IPR004535: IPR000795: IPR004161: IPR 015191; KEGG: afw:Anae109_4150 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 3; SPTR: Selenocysteine-specific translation elongation factor; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor SelB, winge [...] | 0.485 |
| Isop_0783 | selA | Isop_0783 | Isop_1240 | COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896; KEGG: ote:Oter_3934 Fe-S-cluster-containing hydrogenase components 1-like protein; SPTR: Molybdopterin oxidoreductase, iron-sulfur binding subunit. | L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | 0.501 |
| Isop_0783 | selD | Isop_0783 | Isop_2923 | COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896; KEGG: ote:Oter_3934 Fe-S-cluster-containing hydrogenase components 1-like protein; SPTR: Molybdopterin oxidoreductase, iron-sulfur binding subunit. | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.490 |
| Isop_0815 | Isop_2132 | Isop_0815 | Isop_2132 | Cysteine desulfurase IscS; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192: IPR016454; KEGG: cre:CHLREDRAFT_191269 cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; PFAM: Aminotransferase class-V. | COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: rmr:Rmar_1215 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | 0.911 |
| Isop_0815 | selD | Isop_0815 | Isop_2923 | Cysteine desulfurase IscS; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192: IPR016454; KEGG: cre:CHLREDRAFT_191269 cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; PFAM: Aminotransferase class-V. | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.667 |
| Isop_1968 | Isop_0020 | Isop_1968 | Isop_0020 | COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: ace:Acel_1138 SufS subfamily cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Cysteine desulfurases, SufS subfamily; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily. | COGs: COG0492 Thioredoxin reductase; InterPro IPR005982: IPR000103: IPR013027: IPR008255; KEGG: acp:A2cp1_4094 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase. | 0.917 |
| Isop_1968 | selD | Isop_1968 | Isop_2923 | COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010970; KEGG: ace:Acel_1138 SufS subfamily cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Cysteine desulfurases, SufS subfamily; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily. | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.907 |
| Isop_2132 | Isop_0815 | Isop_2132 | Isop_0815 | COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: rmr:Rmar_1215 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | Cysteine desulfurase IscS; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192: IPR016454; KEGG: cre:CHLREDRAFT_191269 cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase; PFAM: Aminotransferase class-V. | 0.911 |
| Isop_2132 | selD | Isop_2132 | Isop_2923 | COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: rmr:Rmar_1215 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V. | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.613 |
| Isop_2922 | gatC | Isop_2922 | Isop_2924 | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: pla:Plav_2158 hypothetical protein; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.413 |
| Isop_2922 | selD | Isop_2922 | Isop_2923 | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: pla:Plav_2158 hypothetical protein; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.773 |
| Isop_3475 | Isop_0783 | Isop_3475 | Isop_0783 | COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR005225: IPR004535: IPR000795: IPR004161: IPR 015191; KEGG: afw:Anae109_4150 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 3; SPTR: Selenocysteine-specific translation elongation factor; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor SelB, winge [...] | COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896; KEGG: ote:Oter_3934 Fe-S-cluster-containing hydrogenase components 1-like protein; SPTR: Molybdopterin oxidoreductase, iron-sulfur binding subunit. | 0.485 |
| Isop_3475 | selA | Isop_3475 | Isop_1240 | COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR005225: IPR004535: IPR000795: IPR004161: IPR 015191; KEGG: afw:Anae109_4150 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 3; SPTR: Selenocysteine-specific translation elongation factor; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor SelB, winge [...] | L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | 0.854 |
| Isop_3475 | selD | Isop_3475 | Isop_2923 | COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR005225: IPR004535: IPR000795: IPR004161: IPR 015191; KEGG: afw:Anae109_4150 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 3; SPTR: Selenocysteine-specific translation elongation factor; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor SelB, winge [...] | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.818 |
| gatC | Isop_2922 | Isop_2924 | Isop_2922 | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: pla:Plav_2158 hypothetical protein; PFAM: protein of unknown function UPF0118; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function DUF20. | 0.413 |
| gatC | selD | Isop_2924 | Isop_2923 | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.409 |
| pyrE | selD | Isop_2956 | Isop_2923 | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. | 0.506 |
| selA | Isop_0783 | Isop_1240 | Isop_0783 | L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. | COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896; KEGG: ote:Oter_3934 Fe-S-cluster-containing hydrogenase components 1-like protein; SPTR: Molybdopterin oxidoreductase, iron-sulfur binding subunit. | 0.501 |