STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Isop_2952Peptidase A24A domain protein; COGs: COG1989 Type II secretory pathway prepilin signal peptidase PulO and related peptidase; InterPro IPR010627; KEGG: plm:Plim_1574 peptidase A24A domain protein; PFAM: peptidase A24A domain protein; SPTR: Peptidase A24A domain protein; PFAM: Bacterial Peptidase A24 N-terminal domain. (493 aa)    
Predicted Functional Partners:
Isop_2822
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR003004: IPR018076; KEGG: plm:Plim_0407 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type IV fimbrial assembly protein PilC; PFAM: Bacterial type II secretion system protein F domain.
 
  
 0.854
Isop_0791
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR003004: IPR018076; KEGG: ank:AnaeK_0718 general secretion pathway protein F; PFAM: Type II secretion system F domain; SPTR: General secretion pathway protein F; PFAM: Bacterial type II secretion system protein F domain.
 
  
 0.852
Isop_2819
Type II secretion system protein E (GspE); COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR003593: IPR007831: IPR001482; KEGG: rba:RB12768 type IV fimbrial assembly protein PilB; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; SPTR: Type IV fimbrial assembly protein PilB; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: general secretory pathway protein E.
 
 
 0.829
Isop_2821
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482: IPR007831; KEGG: plm:Plim_0408 type II secretion system protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: general secretory pathway protein E.
 
 
 0.827
Isop_1022
COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482; KEGG: plm:Plim_0082 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein.
 
 
 0.825
Isop_2820
Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR003593: IPR001482: IPR006321; KEGG: plm:Plim_0409 twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Twitching mobility protein PilT; TIGRFAM: twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT.
 
   
 0.794
Isop_1021
Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321: IPR001482; KEGG: psl:Psta_1744 twitching motility protein; PFAM: type II secretion system protein E; SPTR: Twitching motility protein; TIGRFAM: twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT.
 
   
 0.793
Isop_2953
Abortive infection protein; COGs: COG1668 ABC-type Na+ efflux pump permease component; InterPro IPR003675; KEGG: psl:Psta_1550 abortive infection protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein; PFAM: CAAX amino terminal protease family.
       0.773
Isop_2397
COGs: COG0658 membrane metal-binding protein; InterPro IPR004477: IPR000073; KEGG: rba:RB9840 competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; alpha/beta hydrolase fold; SPTR: Probable competence protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; X-Pro dipeptidyl-peptidase (S15 family); TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.761
Isop_0643
Peptidase A24A prepilin type IV; InterPro IPR000045; KEGG: plm:Plim_1841 peptidase A24A domain protein; PFAM: peptidase A24A prepilin type IV; SPTR: Probable type 4 prepilin-like proteins leader peptide processing enzyme; PFAM: Type IV leader peptidase family.
  
     0.680
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.