STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2979ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: plm:Plim_2404 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; manually curated; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase). (346 aa)    
Predicted Functional Partners:
Isop_0829
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: plm:Plim_1388 ROK family protein; PFAM: ROK family protein; SPTR: ROK protein; PFAM: ROK family.
  
  
 
0.927
Isop_0741
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600: IPR002731; KEGG: psl:Psta_4719 ROK family protein; PFAM: ROK family protein; ATPase BadF/BadG/BcrA/BcrD type; SPTR: Glucokinase; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase).
  
  
 
0.922
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR018189: IPR000169: IPR001672; KEGG: mxa:MXAN_6908 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
    
 0.912
Isop_0737
Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: plm:Plim_0702 aldose 1-epimerase; PFAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase; PFAM: Aldose 1-epimerase.
    
 0.908
Isop_0707
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833: IPR005834: IPR006402; KEGG: spe:Spro_4879 phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Epoxide hydrolase N-terminal domain-like phosphatase.
   
 
  0.906
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.830
xylA
COGs: COG2115 Xylose isomerase; InterPro IPR001998: IPR013452: IPR012307; KEGG: psl:Psta_4262 xylose isomerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Xylose isomerase; SPTR: Xylose isomerase; TIGRFAM: xylose isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; Belongs to the xylose isomerase family.
    
 0.824
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
    
 0.824
Isop_1171
Transketolase; COGs: COG0021 Transketolase; InterProIPR005478: IPR005474: IPR005475: IPR005476: IPR 020826; KEGG: mea:Mex_1p1861 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
  
 
 0.822
Isop_3401
COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: psl:Psta_4168 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
    
 0.814
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
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