STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Isop_2985Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: sin:YN1551_2013 ankyrin; PFAM: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat. (164 aa)    
Predicted Functional Partners:
Isop_3434
Metallophosphoesterase; InterPro IPR004843; KEGG: psl:Psta_1609 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase.
    
 0.881
Isop_0191
KEGG: xcb:XC_0878 protein kinases, catalytic domain; region: PKc_like; cl09925; SPTR: Putative uncharacterized protein.
    
 0.851
Isop_1846
KEGG: psl:Psta_4608 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 0.847
Isop_2908
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: cag:Cagg_1601 histone deacetylase superfamily; PFAM: histone deacetylase superfamily; PRIAM: Histone deacetylase; SPTR: Histone deacetylase superfamily; PFAM: Histone deacetylase domain.
 
 
 0.839
Isop_2003
KR domain protein; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR014031: IPR014043: IPR006163: IPR013968: IPR 009081; KEGG: glo:Glov_2267 polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: KR domain protein; Beta-ketoacyl synthase; Acyl transferase; phosphopantetheine-binding; SPTR: Polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Acyl transferase domain; Phosphopantetheine attachment site; KR domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: acyl carrier protein.
   
 0.816
Isop_0425
AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR003338: IPR004201: IPR003959: IPR003593: IPR 003960: IPR005938; KEGG: mxa:MXAN_2773 AAA family ATPase; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: ATPase, AAA family; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: ATPase family associated with various cellular activities (AAA); Cell division protein 48 (CDC48), N-terminal domain; Cell division protein 48 (CDC48), domain 2; [...]
    
 0.809
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.806
Isop_2535
Major intrinsic protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: ote:Oter_1589 major intrinsic protein; PFAM: major intrinsic protein; SPTR: Major intrinsic protein; PFAM: Major intrinsic protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 0.802
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.783
rpsC
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
    
 
 0.762
Your Current Organism:
Isosphaera pallida
NCBI taxonomy Id: 575540
Other names: I. pallida ATCC 43644, Isosphaera pallida ATCC 43644, Isosphaera pallida DSM 9630, Isosphaera pallida IS1B, Isosphaera pallida str. ATCC 43644, Isosphaera pallida strain ATCC 43644
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.